What is Linifanib used for?

Linifanib is being studied for various cancers, including liver, kidney, colon, breast, and lung cancer, as well as age-related macular degeneration.

How does Linifanib work in the body?

Linifanib works by inhibiting receptors like VEGF, PDGF, and FLT3, which can help stop the signals that allow tumors to grow and develop blood vessels.

Is Linifanib approved for liver cancer?

Linifanib is being investigated for hepatocellular carcinoma (liver cancer) and is currently in Phase 3 clinical trials.

Can Linifanib treat kidney cancer?

Yes, Linifanib is being studied for the treatment of renal cell carcinoma.

What kind of drug is Linifanib?

Linifanib is a small molecule drug that acts as a multi-receptor inhibitor.

Is Linifanib available for breast cancer?

Linifanib is currently being researched for use in breast cancer patients in clinical trials.

linifanib | CAS 796967-16-3 | MPVGZUGXCQEXTM

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Kinase inhibitor

Linifanib is a small molecule drug currently being studied in clinical trials (Phase 3). It works by inhibiting several specific receptors, including those for growth factors and blood vessel growth, to help treat various types of cancer.

How it worksLinifanib works by blocking certain receptors in the body, such as those that help tumors grow new blood vessels or signal cells to divide.

Used for

Hepatocellular carcinoma (liver cancer)Renal cell carcinoma (kidney cancer)Colorectal adenocarcinoma (colon cancer)Rectum cancerBreast cancerMalignant colon neoplasmAge-related macular degenerationNon-small cell lung carcinoma

Conditions

Hepatocellular carcinomaRenal cell carcinomaColorectal adenocarcinomaRectum cancerBreast cancerMalignant colon neoplasmAge-related macular degenerationNon-small cell lung carcinoma

Class

Small moleculeKinase inhibitorVEGF inhibitorPDGF inhibitorFLT3 inhibitorHepaticRenalGastrointestinalRespiratoryOcular

How to take

Linifanib is still in the research and testing phases and is not yet widely approved for general use in all listed conditions.

Talk to your doctor

Questions to ask

·Is Linifanib appropriate for my specific type of cancer?
·What are the potential side effects of Linifanib?
·Are there any clinical trials for Linifanib available?
·How will Linifanib interact with my current medications?

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-26.

How to take

Talk to your doctor

Frequently asked questions (6)