Can I use Reyvow to prevent migraines from happening?

No, Reyvow is only for the acute treatment of a migraine that is already occurring and is not for prevention.

Is it safe to drive after taking Reyvow?

You should not drive or operate machinery until at least 8 hours after taking a dose of Reyvow due to significant impairment risks.

What should I do if I experience symptoms of serotonin syndrome while on Reyvow?

If you experience symptoms consistent with serotonin syndrome, you should stop taking Reyvow.

Can I take Reyvow more than once a day?

No, you should not take more than one dose of Reyvow in a 24-hour period.

Does Reyvow interact with alcohol?

Reyvow may increase the effects of alcohol or other drugs that cause sedation, so use caution.

What are the most common side effects of Reyvow?

The most common side effects reported are dizziness, fatigue, tingling sensations (paresthesia), and sleepiness (sedation).

Can Reyvow affect my heart rate?

Yes, Reyvow may lower your heart rate, especially if taken with other medications that also lower heart rate.

Is Reyvow safe for elderly patients?

Elderly patients may experience more dizziness and higher blood pressure increases, so doctors usually recommend starting with a low dose.

lasmiditan | CAS 439239-90-4 | XEDHVZKDSYZQBF

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Serotonin receptor agonist

Reyvow (lasmiditan) is a prescription medicine used to treat migraine attacks quickly in adults. It works by acting on specific serotonin receptors in the brain. It is meant for acute treatment of a migraine happening now, not for preventing migraines from starting in the future.

How it worksReyvow works as a serotonin 1f (5-HT1f) receptor agonist to help treat migraine symptoms.

Brand names:Reyvow

Used for

Acute treatment of migraine with or without aura in adults

Conditions

Migraine disorder

Class

Serotonin 1f receptor agonistSerotonin receptor agonistNervous system

How to take

FormsOral tablet

RoutesOral

The recommended dose is 50 mg, 100 mg, or 200 mg taken by mouth as needed. Do not take more than one dose in a 24-hour period.

Take the tablets whole; do not split, crush, or chew them. You can take Reyvow with or without food.

Key warnings

·Reyvow can significantly impair your ability to drive or use machinery. Do not drive or operate machinery until at least 8 hours after taking a dose.
·Using Reyvow with alcohol or other drugs that slow down the central nervous system may cause extreme sleepiness or sedation.
·There is a risk of serotonin syndrome, especially if taken with other drugs that increase serotonin levels.
·Using this medication too frequently may lead to medication overuse headaches.

Do not use if

·None listed

Side effects

Common

DizzinessFatigueParesthesia (tingling sensation)Sedation

Serious

·Driving impairment
·Central nervous system depression
·Serotonin syndrome
·Medication overuse headache
·Lowered heart rate

Seek help if

·Serotonin syndrome symptoms
·Severe dizziness or sedation
·Abnormal heart rate

Interactions

·Alcohol and other drugs that cause sedation (CNS depressants)
·Serotonergic drugs (such as SSRIs, SNRIs, TCAs, MAO inhibitors, trazodone, or dextromethorphan)
·Herbal supplements like St. John's Wort
·Drugs that lower heart rate (such as propranolol)

FoodReyvow may be taken with or without food.

AlcoholUse caution when combining Reyvow with alcohol or other drugs that slow down the central nervous system, as it may increase sedation.

Special populations

PregnancyThere is a registry to monitor pregnancy outcomes for women taking Reyvow. There is not enough data to know the exact risks to a developing baby, but animal studies have shown some risks to fetal development.

PediatricThe safety and effectiveness of Reyvow in children have not been established.

GeriatricOlder adults (65+) taking Reyvow may experience dizziness and increases in systolic blood pressure more frequently than younger patients. Doctors should start elderly patients on the lowest possible dose.

Talk to your doctor

Monitor

·Heart rate
·Driving ability/mental alertness
·Symptoms of serotonin syndrome

Questions to ask

·Should I avoid certain medications while taking Reyvow?
·How long should I wait after taking Reyvow before I can drive?
·Is Reyvow safe for me if I have a slow heart rate?
·Can I take Reyvow if I am pregnant?

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-26.