Inhaled corticosteroid
Ciclesonide (brand names Alvesco, Zetonna, Omnaris) is an inhaled steroid used for the long-term maintenance and prevention of asthma in adults and children ages 12 and older. It is not meant to treat sudden asthma attacks or breathing emergencies.
How it worksCiclesonide is a prodrug that turns into an active medicine (des-ciclesonide) once inhaled. This active medicine works by reducing inflammation in the airways by targeting glucocorticoid receptors.
Brand names:ALVESCO, ZETONNA, OMNARIS
How to take
Starting doses usually begin at 80 mcg twice daily, though the highest recommended dose can be up to 320 mcg twice daily depending on previous treatments.
Prime the inhaler before the first use or if it hasn't been used for more than 10 days. After using, rinse your mouth with water and spit it out to prevent mouth infections.
Key warnings
- ·Not for acute asthma attacks or emergencies.
- ·May cause fungal infections in the mouth or throat.
- ·Can cause growth suppression in children; growth should be monitored.
- ·Risk of eye issues like increased pressure or cataracts.
- ·May worsen existing infections like tuberculosis or herpes simplex.
- ·Risk of adrenal gland problems if switching from oral steroids.
Do not use if
- ·Using this for sudden, severe asthma attacks (status asthmaticus).
- ·Known allergy to ciclesonide or any ingredients in the inhaler.
Side effects
Common
Serious
- ·Mouth or throat yeast infections (thrush)
- ·Eye problems like glaucoma or cataracts
- ·Slowed growth in children
- ·Weakened immune system or increased risk of infection
- ·Adrenal gland issues
- ·Thinning of bones
Seek help if
- ·Swelling of lips, tongue, or throat (allergic reaction)
- ·Severe asthma attack
- ·Vision changes
Interactions
- ·Ketoconazole (may increase the amount of medicine in your body)
- ·Tybost
- ·Prezista
- ·Onmel
- ·Paxlovid
- ·Norvir
- ·Evotaz
Special populations
PregnancyThere is limited data on using Alvesco in pregnant women. While animal studies showed no fetal harm at high doses, some changes in weight or bones were seen in rabbits. Use with caution.
PediatricSafe and effective for children 12 years of age and older. It has not been tested in children under 12.
GeriatricNot specifically studied in people over 65, but doctors should use caution and often start with lower doses due to potential changes in how older adults process medicine.
Talk to your doctor
Monitor
- ·Mouth and throat for infections
- ·Child's growth
- ·Vision and eye pressure
- ·Signs of adrenal insufficiency
Questions to ask
- ·How will this affect my child's growth?
- ·Should I be concerned about my eye health?
- ·How do I switch from oral steroids to this inhaler?
- ·What should I do if I develop a mouth sore?
Pharmacokinetics
Practical
OverdoseLong-term overuse may lead to symptoms of hypercorticism (excess hormone levels).
Ingredients
Inactive
Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-25.
