What is Carboprost tromethaamine used for?

It is used to terminate a pregnancy between 13 and 20 weeks or to stop heavy bleeding after giving birth.

Can Carboprost tromethaamine be used at home?

No, it must be used by trained medical staff in a hospital that has intensive care and surgical facilities.

What are the most common side effects of Carboprost tromethaamine?

The most frequent side effects are vomiting, diarrhea, and nausea.

Is Carboprost tromethaamine safe during pregnancy?

It is specifically used to end a pregnancy, and animal studies suggest it can be harmful to a developing embryo or fetus.

Can I take other medicines that cause uterine contractions with Carboprost tromethaamine?

It is not recommended to use Carboprost tromethaamine with other oxytoxic agents as it may increase their activity.

Does Carboprost tromethaamine cause fever?

Yes, some patients may experience a temporary increase in body temperature.

Who should not use Carboprost tromethaamine?

People with pelvic inflammatory disease or active heart, lung, kidney, or liver disease should not use it.

How is Carboprost tromethaamine given?

It is given as an injection deep into the muscle.

carboprost tromethamine | CAS 58551-69-2 | UMMADZJLZAPZAW

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Oxytocic (medication that causes uterine contractions)

Carboprost tromethaamine is an injectable medication used to end a pregnancy between the 13th and 20th weeks or to treat severe bleeding after childbirth that hasn't responded to other treatments. It works by causing the uterus to contract. Because it can cause strong physical reactions, it must only be used in a hospital setting by trained medical professionals.

How it worksThis medicine works by stimulating the muscles of the uterus to contract, similar to labor pains. It also affects the muscles in the digestive tract.

Brand names:HEMABATE

Used for

Ending a pregnancy between the 13th and 20th weeks of gestationTreating severe bleeding after childbirth (postpartum hemorrhage) caused by a lack of uterine tone

Conditions

Second trimester abortion complicationsRefractory postpartum uterine bleeding

Class

OxytocicProstaglandin analogueOxytocic (medication that causes uterine contractions)Reproductive systemGastrointestinal system

How to take

FormsInjection

RoutesIntramuscular (deep into the muscle)

Dosing depends on whether it is being used for pregnancy termination or postpartum bleeding. It is administered by medical professionals using a syringe.

This medication must be used under strict supervision in a hospital with intensive care and surgical facilities available. It should not be used if the fetus has reached the stage of viability (the ability to survive outside the womb).

Key warnings

Carboprost tromethaamine must be used only with strict adherence to recommended doses. It should only be administered by trained medical staff in a hospital that provides immediate intensive care and surgical services.

·Carboprost tromethaamine must be used only with strict adherence to recommended doses. It should only be administered by trained medical staff in a hospital that provides immediate intensive care and surgical services.
·Must be used in a hospital with intensive care and surgery capabilities.
·Strictly follow recommended dosages.
·Not intended for use once a fetus has reached the stage of viability.
·If pregnancy termination fails, other medical methods must be used to complete the process.

Do not use if

·Allergy to carboprost tromethaamine or its components (including anaphylaxis or swelling)
·Acute pelvic inflammatory disease
·Active heart, lung, kidney, or liver disease

Side effects

Common

VomitingDiarrheaNauseaNervousnessNosebleedsSleep problemsHot flashes or flushingHeadacheChills or shivering

Serious

·Chest tightness
·Coughing or wheezing
·Difficulty breathing (dyspnea)
·Blurred vision
·Dizziness
·Possible uterine perforation

Seek help if

·Chest tightness
·Difficulty breathing
·Severe vomiting or diarrhea
·Signs of allergic reaction like swelling

Interactions

·Carboprost tromethaamine may increase the effects of other medications used to cause uterine contractions. Using it with other oxytoxic agents is not recommended.
·Known interactions include ZIOPTAN, IZBA, IYUZEH, VYZULTA, PROSTIN F2 ALPHA, and LATISSSE.

Special populations

PregnancyAnimal studies show this drug can be harmful to embryos or fetuses. While studies do not confirm it causes birth defects in humans, any dose that increases uterine contractions could put a fetus at risk.

PediatricThe safety and effectiveness of Carboprost tromethaamine in children have not been established.

Talk to your doctor

Monitor

·Vomiting and diarrhea
·Body temperature
·Uterine contractions
·Blood pressure

Questions to ask

·Is this medication appropriate for my specific medical history?
·What are the risks of uterine contractions with this drug?
·How will my bleeding be monitored during administration?

Practical

StorageThis medicine must be kept in a refrigerator between 2° to 8° C (36° to 46° F).

Ingredients

Inactive

Sodium hydroxideHydrochloric acidTromethamineSodium chlorideBenzyl alcohol

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-25.