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Cyclin-dependent kinase inhibitor

Alvocidib is a small molecule drug that is being studied for its ability to treat several types of cancer. It works by inhibiting specific proteins called cyclin-dependent kinases, which play a role in how cells grow and divide.

How it worksAlvocidib acts as an inhibitor for various cyclin-dependent kinases (CDK 1, 2, 4, 6, 7, and 9). By blocking these proteins, the drug can interfere with the normal cycle of cell growth and division in cancer cells.

Used for
Prolymphocytic leukemiaKidney cancerLiver cancerEsophageal cancerProstate cancerEndometrial cancerAcute myeloid leukemiaCutaneous melanomaSarcomaChronic lymphocytic leukemiaLymphomaMultiple myelomaLymphoid neoplasmBreast cancer
Conditions
Prolymphocytic leukemiaKidney cancerLiver cancerEsophaeal cancerProstate cancerEndometrial cancerAcute myeloid leukemiaCutaneous melanomaSarcomaChronic lymphocytic leukemiaLymphomaMultiple myelomaLymphoid neoplasmBreast cancer
Class
CDK inhibitorSmall moleculeAntineoplasticCyclin-dependent kinase inhibitorHematologicRenalHepaticDigestiveReproductive

How to take

Alvocidib is currently in clinical development (Max Phase 3) and is not yet widely approved for standard use in all listed conditions. Specific dosing instructions are not available in the provided data.

Talk to your doctor

Questions to ask

  • ·Is Alvocidib appropriate for my specific type of cancer?
  • ·What are the potential risks of taking Alvocidib?
  • ·How will Alvocidib interact with my current medications?

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-25.