What is Volasertib used for?

Volasertib is being studied as a treatment for various cancers, including acute myeloid leukemia, lung cancer, and ovarian cancer.

How does Volasertib work in the body?

Volasertib works by targeting and inhibiting a protein called PLK1, which helps control how cells divide.

Is Volasertib approved for treating lung cancer?

Volasertib is being investigated for non-small cell lung carcinoma in clinical trials, but its approval status varies by condition.

What kind of drug is Volasertib?

Volasertib is classified as a small molecule serine/threonine-protein kinase PLK1 inhibitor.

Can Volasertib treat leukemia?

Yes, research is looking at Volasertib for acute myeloid leukemia and acute monocytic leukemia.

Is Volasertib a natural product?

Yes, according to the drug data, Volasertib is considered a natural product.

Volasertib | CAS 755038-54-1 | SXNJFOWDRLKDSF

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Protein kinase inhibitor

Volasertib (also known as BI 6727) is a small molecule drug being studied for its ability to inhibit a protein called PLK1. It is currently being researched in clinical trials for several types of cancer, including acute myeloid leukemia and non-small cell lung carcinoma.

How it worksVolasertib works by blocking a specific protein called serine/threonine-protein kinase PLK1, which is involved in cell division.

Used for

Acute myeloid leukemiaMyelodysplastic syndromeNon-small cell lung carcinomaNeoplasm (cancer)Ovarian neoplasmMature T-cell and NK-cell non-Hodgkin lymphomaAcute monocytic leukemiaLymphoma

Conditions

Acute myeloid leukemiaMyelodysplastic syndromeNon-small cell lung carcinomaNeoplasmOvarian neoplasmMature T-cell and NK-cell non-Hodgkin lymphomaAcute monocytic leukemiaLymphoma

Class

Small moleculeKinase inhibitorProtein kinase inhibitorImmune systemHematologic system

How to take

This drug is currently in clinical testing phases and is not yet widely approved for general use in all listed conditions. It has reached Phase 3 clinical trials for acute myeloid leukemia.

Talk to your doctor

Questions to ask

·Is Volasertib appropriate for my type of cancer?
·What are the potential risks of Volasertib?
·How is Volasertib administered in clinical trials?

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-26.

How to take

Talk to your doctor

Frequently asked questions (6)