What was Suprofen used for?

Suprofen was used to treat rheumatic diseases.

Is Suprofen still available?

No, Suprofen has been withdrawn from the market.

What are the main side effects of Suprofen?

Commonly reported side effects include flank pain and decreased kidney function.

Why was Suprofen withdrawn?

The drug was withdrawn due to concerns regarding kidney (nephrotoxicity) and musculoskeletal toxicity.

How does Suprofen work in the body?

Suprofen acts as a cyclooxygenase inhibitor to fight inflammation.

Can Suprofen be applied to the skin?

Yes, the drug was categorized as a topical medication.

Suprofen | CAS 40828-46-4 | MDKGKXOCJGEUJW

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Anti-inflammatory

Suprofen is an anti-inflammatory drug that works by inhibiting the cyclooxygenase enzyme. It was originally used for rheumatic diseases but has since been withdrawn from the market due to safety concerns.

How it worksSuprofen works by blocking an enzyme called cyclooxygenase, which helps reduce inflammation.

Used for

rheumatic disease

Conditions

rheumatic disease

Class

Anti-InflammatoryCyclooxygenase inhibitorAnti-inflammatorymusculoskeletalrenal

How to take

Formstopical

Routestopical

This drug has been withdrawn from the market.

Key warnings

·Suprofen was associated with flank pain and decreased kidney function.
·The drug has been withdrawn due to risks of kidney and musculoskeletal toxicity.

Side effects

Common

flank paindecreased kidney function

Serious

·kidney toxicity
·musculoskeletal toxicity

Seek help if

·flank pain
·changes in kidney function

Talk to your doctor

Monitor

·kidney function
·flank pain

Questions to ask

·What are the risks of kidney damage from anti-inflammatories?
·Are there safer alternatives for my rheumatic disease?

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-26.

How to take

Key warnings

Side effects

Talk to your doctor

Frequently asked questions (6)