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Anti-cancer (antineoplastic)
Semustine is an anti-cancer drug (antineoplastic) that works by linking DNA strands together. It has been studied for use in treating various types of tumors, including colorectal cancer, glioblastoma, and graft versus host disease.
How it worksSemustine works as a DNA cross-linking agent, which means it attaches to DNA to prevent cancer cells from growing.
Used for
Colorectal cancerGlioblastoma (a type of brain tumor)Graft versus host diseaseGeneral neoplasms (tumors)
Conditions
NeoplasmsColorectal carcinomaGraft versus host diseaseGlioblastoma
Class
Anti-cancerAntineoplasticDNA cross-linking agentAnti-cancer (antineoplastic)DNA
How to take
The provided data does not specify the exact dosage or the method of administration (such as oral or injection).
Key warnings
- ·Semustine has shown evidence of being a mutagen and may have the potential to induce cancer in humans.
Side effects
Serious
- ·Potential for causing cancer (carcinogenic potential)
Seek help if
- ·Signs of potential cancer development
- ·Severe reactions to treatment
Talk to your doctor
Monitor
- ·Cancer development risks due to mutagenicity
Questions to ask
- ·What is the specific dosage of Semustine I will be taking?
- ·How will Semustine be administered (oral or injection)?
- ·What are the long-term cancer risks associated with Semustine?
- ·How will Semustine affect my DNA and overall health?
Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-26.