What is norethynodrel used for?

Norethynodrel is a progestin used to treat conditions related to hormone levels.

How does norethynodrel work in my body?

It works as a progesterone receptor agonist, meaning it mimics the effects of the natural hormone progesterone.

Can norethynodrel cause liver problems?

Studies have looked at various liver-related effects for this drug, including potential issues like hepatitis or cholestasis.

Is norethynodrel a natural product?

Yes, norethynodrel is classified as a natural product.

How is norethynodrel taken?

It is typically taken by mouth as an oral medication.

Is norethynodrel known to cause DNA mutations?

Research, including Ames tests, has consistently shown negative results for mutagenicity in various studies.

Norethynodrel | CAS 68-23-5 | ICTXHFFSOAJUMG

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Progestin

Norethynodrel is a type of hormone medication known as a progestin. It works by acting on progesterone receptors in the body. It is primarily used in hormone-related therapies and was first approved in 1961.

How it worksNorethynodrel works by mimicking the hormone progesterone, binding to progesterone receptors to produce its effects.

Used for

Hormone-related conditions (as a progestin)

Conditions

Progestin-related conditions

Class

ProgestinHormoneEndocrine system

How to take

FormsOral

RoutesOral

Norethynodrel is a small molecule and a natural product derivative used as a progestin agonist.

Key warnings

·Potential for liver toxicity as indicated by various hepatic activity studies.

Side effects

Serious

·Liver-related issues (noted in chemical activity studies including potential hepatotoxicity, cholestasis, and hepatitis)

Seek help if

·If you experience signs of liver issues such as yellowing of the skin or eyes.

Talk to your doctor

Monitor

·Liver function

Questions to ask

·What are the potential liver-related side effects of norethynodrel?
·How will norethynodrel affect my hormone levels?

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-26.

How to take

Key warnings

Side effects

Talk to your doctor

Frequently asked questions (6)