What is Alocril used for?

Alocril is used to treat eye itching caused by allergic conjunctivitis.

How often should I use Nedocromil sodium eye drops?

The recommended dose is one or two drops in each eye twice a day.

Should I stop using Alocril once my eye itching goes away?

No, you should continue using it throughout the time you are exposed to allergens, even if symptoms disappear.

What are the most common side effects of Alocril?

The most common side effect is headache, followed by eye burning, stinging, irritation, an unpleasant taste, or nasal congestion.

Is Alocril safe to use during pregnancy?

Because there aren't enough studies on pregnant women, you should only use it if your doctor says it is absolutely necessary.

Can I use Nedocromil sodium if I am breastfeeding?

You should use caution because it is unknown if the drug passes into human breast milk.

Is Alocril safe for children under 3?

The safety and effectiveness for children under 3 years old have not been proven.

How does Alocril work in the eyes?

It is a mast cell stabilizer that prevents cells from releasing the chemicals that trigger allergic reactions.

Nedocromil Sodium | CAS 69049-74-7 | JQEKDNLKIVGXAU

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Anti-Allergic (prophylactic)

Nedocromil sodium (brand names Alocril or Tilade) is an eye drop used to treat itching caused by allergic conjunctivitis. It works as a mast cell stabilizer to prevent the release of substances that cause allergy symptoms. It is applied directly to the eyes as a liquid solution.

How it worksNedocromiil sodium is a mast cell stabilizer. It works by stopping cells from releasing the chemicals that cause allergic reactions.

Brand names:TILADE, ALOCRIL

Used for

Itching from allergic conjunctivitis

Conditions

Allergic conjunctivitis

Class

Anti-allergyMast cell stabilizerAnti-Allergic (prophylactic)Ocular

How to take

FormsOphthalmic solution (eye drops)

RoutesTopical (eyes)

The usual dose is one or two drops in each eye, twice a day.

You should use Alocril regularly at set intervals. Even if your symptoms go away, you should keep using it as long as you are exposed to pollen or the allergen that causes your reaction.

Key warnings

·Do not use Alocril if you have a known allergy to nedocromil sodium or any of its ingredients.

Do not use if

·People who are hypersensitive (allergic) to nedocromil sodium or any other ingredients in the solution.

Side effects

Common

HeadacheEye burningEye irritation or stingingUnpleasant tasteNasal congestion

Serious

·Asthma
·Conjunctivitis
·Eye redness
·Sensitivity to light (photophobia)
·Rhinitis

Seek help if

·If you experience asthma or severe eye redness, contact a professional.

Special populations

PregnancyAnimal studies showed no harm to fetuses, but there are no controlled studies in pregnant women. Use Alocril during pregnancy only if your doctor decides it is clearly necessary.

BreastfeedingIt is unknown if this drug passes into human breast milk. Use caution if you are breastfeeding.

PediatricThe safety and effectiveness of Alocril in children under 3 years old have not been established.

GeriatricNo major differences in safety or effectiveness were found between elderly patients and younger patients.

Talk to your doctor

Monitor

·Headaches
·Eye irritation or stinging
·Asthma symptoms
·Eye redness

Questions to ask

·Should I continue using Alocril even when my eyes feel fine?
·Is it safe for me to use this while pregnant or nursing?
·Can I use this if I have asthma?

Pharmacokinetics

BioavailabilityLess than 4% of the total dose is absorbed into the bloodstream after multiple uses.

MetabolismIt is not metabolized.

ExcretionIt is eliminated primarily through urine (70%) and feces (30%).

Practical

StorageStore between 2º–25º C (36º–77º F).

Ingredients

Inactive

Edetatate disodiumpurified watersodium chlorideBenzalkonium chloride

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-25.