Nutritional solution (Amino Acid/Lipid emulsion)
Kabiven is a nutritional solution used through an IV (intravenous) line to provide essential calories, protein, electrolytes, and fatty acids to adults who cannot get enough nutrition by mouth or through a feeding tube. It is used to prevent nutritional deficiencies or manage protein imbalances in patients requiring parenteral nutrition.
Brand names:Kabiven
How to take
Dosage should be determined by a healthcare professional based on the patient's specific needs and renal function. It must be infused into a central vein using a 1.2 micron in-line filter.
Kabiven must be administered into a central vein only. It should be used with a dedicated line and a 1.2 micron filter to prevent complications like air embolisms or blockages. It should not be mixed with certain antibiotics like ceftriaxone in the same line or even in the same patient if they are neonates, as this can cause fatal precipitates in the blood.
Key warnings
- ·Risk of liver disease with use lasting longer than 2 weeks
- ·Risk of fatal drug interactions (specifically with ceftriaxon/calcium) in newborns
- ·Risk of respiratory distress or pulmonary embolism
- ·Risk of severe allergic reactions to ingredients like egg, soybean, or peanut
Do not use if
- ·Neonates (28 days or younger) receiving ceftriaxone
- ·People with known allergies to egg, soybean, peanut, or any Kabiven ingredients
- ·People with severe lipid metabolism disorders (very high triglycerides > 1,000 mg/dL)
Side effects
Common
Serious
- ·Rapid infusion in infants can cause breathing problems, metabolic acidosis, or death
- ·Liver disease from long-term use (more than 2 weeks)
- ·Blood clots or breathing issues due to particles in the lungs
- ·Severe allergic reactions
- ·Fatal precipitation of drugs (like ceftriaxone) in the bloodstream
Seek help if
- ·Respiratory distress
- ·Signs of an allergic reaction
- ·Signs of liver dysfunction
Interactions
- ·Warfarin and other blood thinners: Kabiven may reduce the effectiveness of these drugs; blood monitoring is required.
- ·Ceftriaxone: Mixing Kabiven with ceftriaxone (especially in neonates) can cause dangerous particles to form in the blood, lungs, or kidneys. These should not be given through the same line or even close together without thorough flushing.
Special populations
PregnancyThere is limited data on using Kabiven in pregnant women. While the drug itself hasn't been studied for birth defect risks in animals, severe malnutrition in a pregnant woman can lead to preterm birth or low birth weight. A doctor should decide if the nutritional benefits outweigh the risks.
PediatricKabiven is not recommended for children under 2 years old because the formula does not meet their specific nutritional needs. In infants and neonates, rapid infusion can be fatal and there is a risk of aluminum toxicity.
GeriatricThere isn't enough data on patients over 65, but doctors usually start with a lower dose because older adults may have different liver, kidney, or heart functions.
Talk to your doctor
Monitor
- ·Liver function tests
- ·Triglyceride levels
- ·Signs of respiratory distress
- ·Signs of hypersensitivity/allergic reactions
Questions to ask
- ·Is this nutrition solution appropriate for my specific nutritional needs?
- ·How will my liver function be monitored during use?
- ·Are there any specific allergies I should be concerned about?
- ·How should this be administered with my other medications?
Practical
OverdoseIf an overdose occurs, stop the infusion immediately to let the fats clear from the blood. The effects are usually reversible once the infusion stops, though medical intervention may be needed.
Ingredients
Allergens
Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-26.
