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Tyrosine-protein kinase inhibitor

Gilteritinib fumarate is an oral small molecule medication used to treat certain types of myeloid leukemia, specifically acute myeloid leukemia. It works by inhibiting specific tyrosine-protein kinase receptors (FLT3 and UFO) to help fight cancer cells.

How it worksGilteritinib fumarate works by blocking certain proteins called FLT3 and UFO that help cancer cells grow and survive.

Used for
acute myeloid leukemiamyeloid leukemia
Conditions
acute myeloid leukemiamyeloid leukemia
Class
tyrosine-protein kinase inhibitorTyrosine-protein kinase inhibitor

How to take

Formsoral
Routesoral

The input specifies the drug is an oral small molecule, but does not provide specific dosing instructions.

Key warnings

Gilteritinib fumarate carries a black box warning regarding carcinogenicity (the potential to cause cancer).

  • ·Gilteritinib fumarate carries a black box warning regarding carcinogenicity (the potential to cause cancer).
  • ·Carcinogenicity

Side effects

Serious

  • ·carcinogenicity

Seek help if

  • ·Signs of cancer-related complications

Talk to your doctor

Questions to ask

  • ·Is Gilteritinib fumarate appropriate for my type of leukemia?
  • ·What are the cancer-related risks associated with this drug?
  • ·How will this medication interact with my current treatments?

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-26.