What is fenoprofen calcium used for?

Fenoprofen calcium is used to relieve mild to moderate pain and manage symptoms of rheumatoid arthritis and osteoarthritis.

Can fenoprofen calcium cause heart problems?

Yes, fenoprofen calcium can increase the risk of serious cardiovascular events, including heart attack and stroke, which can be fatal.

Does fenoprofen calcium cause stomach bleeding?

Yes, this medication can cause serious stomach or intestinal issues like bleeding, ulcers, and perforation, which can be life-threatening.

What is the normal dose of fenoprofen calcium for pain?

For mild to moderate pain, the typical dose is 200 mg taken orally every 4 to 6 hours as needed.

Can I take fenoprofen calcium if I have asthma?

You should not take fenoprofen calcium if you have a history of asthma or hives after taking aspirin or other NSAIDs.

Is fenoprofen calcium safe to take during pregnancy?

No, it can cause kidney problems in the baby or cause a heart vessel to close too early; it should be avoided, especially after 20-30 weeks of pregnancy.

What should I do if I take too much fenoprofen calcium?

If an overdose occurs, seek medical help immediately; symptoms can include nausea, vomiting, and stomach pain, but more serious issues like kidney failure can occur.

Are there side effects for elderly patients using fenoprofen calcium?

Yes, elderly patients face a higher risk of serious heart, stomach, and kidney problems compared to younger users.

Fenoprofen Calcium | CAS 71720-56-4 | LZPBLUATTGKZBH

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Nonsteroidal anti-inflammatory drug (NSAID)

Fenoprofen calcium is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve mild to moderate pain and reduce the signs and symptoms of rheumatoid arthritis and osteoarthritis. It works by inhibiting the enzyme cyclooxygenase to reduce inflammation and pain.

How it worksIt works as a cyclooxygenase inhibitor to reduce inflammation and pain.

Brand names:FENOPROFEN CALCIUM

Used for

Relief of mild to moderate pain in adultsRelief of rheumatoid arthritis symptomsRelief of osteoarthritis symptoms

Conditions

PainRheumatoid arthritisOsteoarthritis

Class

NSAIDAnalgesicAnti-inflammatoryNonsteroidal anti-inflammatory drug (NSAID)CardiovascularGastrointestinalRenalHepaticHematologicNervous system

How to take

FormsOral

RoutesOral

For mild to moderate pain, the dose is 200 mg every 4 to 6 hours as needed. For arthritis, the dose is 400 to 600 mg taken 3 or 4 times a day. Do not exceed 3,200 mg in a single day.

Always use the lowest effective dose for the shortest time possible to meet your treatment goals.

Key warnings

Fenoprofen calcium carries serious warnings regarding the risk of fatal cardiovascular events like heart attack and stroke, as well as serious stomach and intestinal issues like bleeding, ulcers, and perforation.

·Fenoprofen calcium carries serious warnings regarding the risk of fatal cardiovascular events like heart attack and stroke, as well as serious stomach and intestinal issues like bleeding, ulcers, and perforation.
·Increased risk of serious heart-related events like heart attack or stroke.
·Increased risk of stomach bleeding, ulcers, and intestinal holes which can be fatal.
·Potential for liver toxicity.
·Risk of high blood pressure.
·Risk of worsening heart failure or causing fluid buildup (edema).
·Risk of kidney damage, especially in those with existing kidney or liver issues.

Do not use if

·Known allergy to fenoprofen or any of its ingredients.
·History of asthma, hives, or allergic reactions after taking aspirin or other NSAIDs.
·Use during or immediately after coronary artery bypass graft (CABG) surgery.

Side effects

Common

IndigestionHeadacheSleepinessNauseaDizzinessConstipationNervousnessWeaknessSwelling in the hands or feet

Serious

·Heart attack or stroke
·Stomach bleeding, ulcers, or holes in the stomach/intestines
·Liver problems
·High blood pressure
·Heart failure or fluid buildup
·Kidney problems
·Severe allergic reactions or skin reactions
·Blood cell changes

Seek help if

·Chest pain
·Shortness of breath
·Weakness
·Slurred speech
·Signs of stomach bleeding

Interactions

·Anticoagulants (like warfarin) can increase the risk of bleeding.
·Antiplatelet drugs (like aspirin) can increase bleeding risk.
·SSRIs and SNRIs (certain antidepressants) may increase the risk of bleeding.
·Certain blood pressure medications may not work as well while taking this drug.

Special populations

PregnancyTaking fenoprofen calcium during pregnancy, especially between 20 and 30 weeks, can cause serious issues for the baby, such as kidney problems or premature closure of a heart vessel. Avoid use during the 30th week of pregnancy or later.

PediatricThe safety and effectiveness of fenoprofen calcium in children under 18 have not been established.

GeriatricOlder adults are at a higher risk for serious heart, stomach, and kidney reactions. If used, start with a low dose and monitor closely.

Talk to your doctor

Monitor

·Blood pressure
·Liver function tests
·Renal function
·Signs of stomach bleeding
·Signs of heart attack or stroke

Questions to ask

·Is fenoprofen calcium safe for my heart health?
·Will this interact with my blood pressure medication?
·How will this affect my kidney function?
·Is this safe to take with my current blood thinners?

Pharmacokinetics

Protein bindingHigh protein binding (noted in overdose section)

Practical

OverdoseSymptoms of overdose may include drowsiness, nausea, vomiting, and stomach pain. Serious cases can involve kidney failure or coma. There is no specific antidote; treatment focuses on supportive care.

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-26.