What is ROXADUSTAT used for?

ROXADUSTAT is being researched to treat anemia, chronic kidney disease, and myelodysplastic syndrome.

How does ROXADUSTAT work in the body?

ROXADUSTAT works by inhibiting hypoxia-inducible factor prolyl hydroxylase.

Can ROXADUSTAT treat kidney disease?

Yes, chronic kidney disease and general kidney disease are listed as indications for ROXADUSTAT.

Is ROXADUSTAT used for heart issues?

Research has looked into using ROXADUSTAT for ST Elevation Myocardial Infarction.

What is the status of ROXADUSTAT research?

ROXADUSTAT has reached phase 4 in some areas of study, indicating advanced research stages.

FG 4592 | CAS 808118-40-3 | YOZBGTLTNGAVFU

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Hypoxia-inducible factor prolyl hydroxylase inhibitor

ROXADUSTAT is a small molecule drug that works by inhibiting the enzyme hypoxia-inducible factor prolyl hydroxylase. It is being studied for its potential to treat conditions like chronic kidney disease and anemia.

How it worksROXADUSTAT works by blocking an enzyme called hypoxia-inducible factor prolyl hydroxylase, which helps the body respond to low oxygen levels.

Used for

Chronic kidney diseaseAnemiaMyelodysplastic syndromeST Elevation Myocardial InfarctionKidney disease

Conditions

AnemiaChronic kidney diseaseMyelodysplastic syndromeST Elevation Myocardial InfarctionKidney disease

Class

Hypoxia-inducible factor prolyl hydroxylase inhibitorRenalHematologic

How to take

The input data does not specify the administration route (oral, injection, etc.) or specific dosing instructions for ROXADUSTAT.

Talk to your doctor

Questions to ask

·How might ROXADUSTAT affect my kidney function?
·What are the potential benefits of ROXADUSTAT for my anemia?
·Are there known interactions between ROXADUSTAT and my current medications?

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-26.

How to take

Talk to your doctor

Frequently asked questions (6)