What is Eletriptan hydrobromide used for?

It is used for the quick treatment of migraine attacks in adults, with or without aura.

Can I take Eletriptan hydrobromide to prevent migraines?

No, Eletriptan hydrobromide is not intended to prevent migraine attacks; it is only for treating them once they start.

What is the maximum dose of Eletriptan hydrobromide in one day?

You should not exceed a total of 80 mg of Eletriptan hydrobromide in any 24-hour period.

Can I take Eletriptan hydrobromide if I have heart disease?

No, people with a history of coronary artery disease or heart spasms should not use this medication.

Is it safe to breastfeed while taking Eletriptan hydrobromide?

Eletriptan passes into milk; it is recommended to avoid breastfeeding for 24 hours after taking a dose.

What are the most common side effects of Eletriptan hydrobromide?

The most frequent side effects are weakness, nausea, dizziness, and sleepiness.

Can I take Eletriptan hydrobromide with other migraine medicines?

You must not take Eletriptan hydrobromide within 24 hours of using other 5-HT 1 agonists or ergot-type drugs.

What should I do if I experience chest pain while taking Eletriptan hydrobromide?

Chest, throat, or jaw pain should be evaluated, as it may indicate serious heart issues.

Eletriptan Hydrobromide | CAS 177834-92-3 | UTINOWOSWSPFLJ

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Serotonin receptor agonist (Triptan)

Eletriptan hydrobromide (brand name RELPAX) is a prescription tablet used to treat the sudden onset of migraine headaches in adults. It works by acting on specific serotonin receptors to shrink swollen blood vessels in the brain and stop the release of inflammatory substances. It should not be used to prevent migraines or to treat cluster headaches.

How it worksEletriptan hydrobromide works by binding to serotonin receptors (5-HT 1B, 1D, and 1F). This action constricts blood vessels in the head and prevents the release of chemicals that cause migraine pain.

Brand names:RELPAX

Used for

Acute treatment of migraine with or without aura in adults

Conditions

Migraine

Class

TriptanSerotonin receptor agonistSerotonin receptor agonist (Triptan)Nervous systemCardiovascular system

How to take

FormsOral tablet

RoutesOral

The standard single dose is 20 mg or 40 mg. If the migraine does not go away or comes back, you may take a second dose at least 2 hours after the first. Do not take more than 80 mg in a 24-hour period.

Do not use this medication to prevent migraines. It is only for treating a migraine once it has started.

Key warnings

·Eletriptan hydrobromide may cause serious heart-related issues like heart attack or chest pain, even in people without a history of heart disease.
·Stop use and contact a doctor immediately if you experience heart rhythm changes, stroke symptoms, or signs of serotonin syndrome.
·Using this drug too often can lead to medication overuse headaches.

Do not use if

·History of coronary artery disease or heart spasms
·Wolff-Parkinson-White syndrome or other heart conduction disorders
·History of stroke or transient ischemic attack
·Peripheral vascular disease or ischemic bowel disease
·Uncontrolled high blood pressure
·Known hypersensitivity to eletriptan hydrobromide

Side effects

Common

Weakness (asthenia)NauseaDizzinessSleepiness (somnolence)

Serious

·Heart attack or chest pain
·Heart rhythm problems
·Stroke or brain bleeding
·Severe allergic reactions (swelling or difficulty breathing)
·Serotonin syndrome (when taken with certain antidepressants)
·High blood pressure
·Gastrointestinal issues

Seek help if

·Chest, throat, neck, or jaw pain
·Signs of a stroke
·Heart palpitations or irregular heartbeat
·Difficulty breathing or swelling of the face/throat

Interactions

·Do not use within 24 hours of other 5-HT 1 agonists or ergot-type medications (like dihydroergotamine).
·Do not use within 72 hours of taking potent CYP3A4 inhibitors like ketoconazole or ritonavir.
·Taking this with certain antidepressants (SSRIs, SNRIs, TCAs, or MAOIs) may cause serotonin syndrome.

FoodEletriptan hydrobromide can be taken with or without food. Taking it with a high-fat meal may increase the amount of drug in your body by 20% to 30%.

Special populations

PregnancyHuman data is limited, but animal studies showed risks to fetal development. The benefits of use should be weighed against potential risks to the baby.

BreastfeedingEletriptan is passed into breast milk. To minimize baby's exposure, avoid breastfeeding for 24 hours after taking the medication.

PediatricSafety and effectiveness in children and adolescents have not been established.

GeriatricIn older adults, this medication may increase blood pressure more than in younger people.

Talk to your doctor

Monitor

·Blood pressure
·Heart rhythm
·Frequency of migraine attacks

Questions to ask

·Is my migraine diagnosis confirmed before starting Eletripan?
·Do I have any underlying heart conditions that make this unsafe?
·How will this interact with my current antidepressant?
·Should I avoid certain foods while taking this medication?

Pharmacokinetics

OnsetPeak plasma levels occur about 1.5 to 2 hours after dosing

Half-lifeApproximately 4 hours

BioavailabilityApproximately 50%

Protein bindingApproximately 85%

MetabolismN-demethylated meta-...

Practical

OverdoseIf an overdose occurs, monitor the patient for at least 20 hours. There is no specific antidote.

Ingredients

Allergens

lactose

Inactive

anhydrous lactosecroscarmellose sodiumFD & C Yellow No. #6 aluminum lakehypromelloselactose monohydratemagnesium stearatemicrocrystalline cellulosepovidonetitanium dioxidetriacetinD & C Yellow #10 aluminum lakeFD & C Blue #2 aluminum lakeferric oxide yellowferric oxide red

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-25.