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Beta-secretase 1 inhibitor

ELENBECESTAT (also known as E-2609 or E26) is a small molecule drug currently being studied in clinical trials. It works as a beta-secretase 1 inhibitor, which is a mechanism being researched for the treatment of Alzheimer disease.

How it worksIt works by inhibiting beta-secretase 1.

Used for
Alzheimer disease
Conditions
Alzheimer disease
Class
Beta-secretase 1 inhibitorNervous system

How to take

This drug is currently in Phase 3 clinical trials and is not yet FDA-approved for general use.

Talk to your doctor

Questions to ask

  • ·Is ELENBECESTAT part of a clinical trial I can join?
  • ·How does a beta-secretase 1 inhibitor work for Alzheimer's?

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-25.