What is Diflorasone Diacetate used for?

It is used to help relieve the itching and swelling caused by certain skin conditions that respond to steroids.

How often should I apply Diflorasone Diacetate ointment?

You should apply a thin film to the affected area one to three times a day, depending on the severity of your skin issue.

Can I cover the area where I applied Diflorasone Diacetate with a bandage?

Yes, occlusive dressings can be used for conditions like psoriasis, but they increase how much medicine your body absorbs.

What should I do if I get an infection while using Diflorasone Diacetate?

If an infection develops, stop using any coverings or dressings and seek treatment for the infection.

Is Diflorasone Diacetate safe to use during pregnancy?

It should only be used during pregnancy if your doctor decides the benefits outweigh the potential risks to the fetus.

Are there side effects for children using Diflorasone Diacetate?

Children are at a higher risk of absorbing too much medicine, which can affect their hormones or cause skin stretch marks.

Can Diflorasone Diacetate cause skin thinning?

Yes, skin atrophy (thinning) is a reported side effect of using topical corticosteroids.

What happens if I use too much Diflorasone Diacetate?

Applying too much can lead to the medicine being absorbed into your body in amounts large enough to cause systemic effects.

Diflorasone Diacetate | CAS 33564-31-7 | BOBLHFUVNSFZPJ

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Topical Corticosteroid (Anti-inflammatory)

Diflorasone diacetate is a topical steroid ointment used to reduce swelling, redness, and itching caused by certain skin conditions. It works by acting on glucocorticoid receptors in the skin to calm inflammation.

How it worksIt works as a glucocorticoid receptor agonist to reduce inflammation and itching in the skin.

Brand names:FLORONE, PSORCON, FLORONE E, PSORCON E

Used for

Relief of skin inflammationRelief of skin itchingTreatment of corticosteroid-responsive skin diseases

Conditions

PsoriasisCorticosteroid-responsive dermatoses

Class

CorticosteroidAnti-inflammatoryTopical Corticosteroid (Anti-inflammatory)Integumentary (Skin)

How to take

FormsOintment

RoutesTopical (applied to the skin)

Apply a thin layer to the affected area 1 to 3 times daily, depending on how severe the condition is.

For stubborn conditions like psoriasis, your doctor might suggest using occlusive dressings (coverings). If an infection starts while using dressings, stop using them and contact a doctor for antimicrobial treatment.

Key warnings

·Do not use if you have a history of allergic reactions to any ingredients in this product.
·Using occlusive dressings (covering the area) can increase how much medicine is absorbed into your body.
·If an infection develops, stop using dressings immediately.

Do not use if

·Do not use if you are allergic to any of the ingredients in this ointment.

Side effects

Common

BurningItchingIrritationDrynessAcne-like eruptionsSkin thinning (atrophy)Changes in skin color (lightening or darkening)Hair growth in the treated area

Serious

·Skin infections
·Skin thinning or stretch marks
·Systemic absorption leading to body-wide effects

Seek help if

·Signs of an infection
·Severe skin irritation

Special populations

PregnancyUse during pregnancy only if the potential benefit to you outweighs the possible risk to the baby. High doses of steroids in animal studies have shown risks to developing babies.

BreastfeedingIt is not known if this medicine passes into breast milk in large amounts, but you should use caution when applying it while nursing.

PediatricThe safety of diflorasone diacetate in children has not been fully established. Children are at a higher risk of absorbing too much medicine, which can lead to hormone imbalances or growth issues.

Geriatricnull

Talk to your doctor

Monitor

·Signs of skin infection
·Skin thinning or stretch marks
·Changes in skin color
·Systemic symptoms

Questions to ask

·Is this safe for my specific skin condition?
·Should I avoid using bandages over the ointment?
·How will this affect my child's hormone levels?

Pharmacokinetics

BioavailabilityAbsorption is influenced by the skin barrier, the vehicle used, and whether occlusive dressings are applied.

Protein bindingCorticosteroids are bound to plasma proteins once absorbed.

Practical

OverdoseApplying too much can cause the medicine to be absorbed into the bloodstream, which may cause body-wide side effects.

StorageStore between 68° to 77°F (20° to 25°C).

Ingredients

Inactive

Propylene glycolGlyceryl monostearateWhite petrolatum

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-25.