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Vasopressin receptor antagonist

Conivaptan hydrochloride is a small molecule drug that works by blocking vasopressin V1a and V2 receptors. It has been studied for use in treating conditions like heart failure and low sodium levels (hyponatremia).

How it worksThis medication works by blocking specific receptors (V1a and V2) that respond to the hormone vasopressin.

Used for
Heart failureLow sodium levels (hyponatremia)Liver disease
Conditions
Heart failureHyponatremiaLiver diseases
Class
Vasopressin V1a receptor antagonistVasopressin V2 receptor antagonistVasopressin receptor antagonistCardiovascular systemRenal system

How to take

Routesparenteral

The provided data indicates this drug is administered via parenteral routes (such as injection) rather than orally. It is currently in a late stage of development (Phase 4).

Talk to your doctor

Questions to ask

  • ·Is Conivaptan hydrochloride the right treatment for my heart failure?
  • ·How will this medication affect my sodium levels?
  • ·What are the risks of using a vasopressin antagonist?

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-25.