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Integrin antagonist
CIlengitide is a protein-based drug currently being studied in clinical trials. It works by blocking specific proteins called integrin alpha-V/beta-3 and alpha-V/beta-5, which are involved in how certain cells behave.
How it worksCIlengitide acts as an antagonist to integrin alpha-V/beta-3 and alpha-V/beta-5, meaning it blocks these specific targets in the body.
Used for
Glioblastoma multiformeProstate cancerCerebral astrocytomaGliosarcomaCentral nervous system cancerAnaplastic astrocytomaAnaplastic oligodendrogliomaNon-small cell lung carcinomaMelanomaSarcomaChronic myeloproliferative disorderKidney diseaseDiffuse intrinsic pontine gliomaCentral nervous system neoplasmsMyelodysplastic syndrome
Conditions
GlioblastomaProstate cancerMelanomaLung cancerKidney disease
Class
Integrin antagonistProteinCentral Nervous SystemRenal
How to take
CIlengitide is currently in various stages of clinical research (Max Phase 1.0 to 3.0) and is not yet a standard approved treatment for these conditions in all cases.
Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-25.
