What is AMCENESTRANT used for?

AMCENESTRANT is being studied to treat various forms of cancer, such as breast cancer and angiosarcoma.

How does AMCENESTRANT work?

It works as an estrogen receptor alpha degrader, which helps target specific estrogen receptors.

Is AMCENESTRANT approved for breast cancer?

It is currently in Phase 3 clinical trials for breast cancer and is not yet widely available.

Can AMCENESTRANT treat triple-negative breast cancer?

Yes, it is being investigated for use in treating triple-negative breast cancer.

What is the mechanism of action for Amcenestra?

Amcenestra acts by degrading estrogen receptor alpha.

Is AMCENESTRANT a small molecule drug?

Yes, AMCENESTRANT is classified as a small molecule.

Amcenestrant | CAS 2114339-57-8 | KISZAGQTIXIVAR

Loading compound...

Estrogen receptor alpha degrader

AMCENESTRANT (also known as Amcenestra) is a small molecule drug currently in clinical development (Phase 3). It works as an estrogen receptor alpha degrader, meaning it helps break down specific estrogen receptors in the body. It is being studied for various types of breast cancer, including triple-negative breast cancer and angiosarcoma.

How it worksAMCENESTRANT works by breaking down estrogen receptor alpha in the body.

Used for

Breast cancerBreast neoplasmAngiosarcomaTriple-negative breast cancer

Conditions

Breast cancerAngiosarcomaTriple-negative breast cancer

Class

Small moleculeEstrogen receptor alpha degraderEndocrine system

How to take

This drug is currently in clinical trials (Phase 3) and is not yet FDA-approved for general use.

Talk to your doctor

Questions to ask

·Is AMCENESTRANT part of a clinical trial I can join?
·How does an estrogen receptor alpha degrader work?
·What are the expected benefits of AMCENESTRANT for breast cancer?

Educational summary derived from FDA labeling, AI-assisted. Not medical advice — consult a healthcare professional. Updated 2026-04-26.

How to take

Talk to your doctor

Frequently asked questions (6)